Admenta 5 mg (Memantine)

Description

Admenta 5 mg is a Memantine, a drug that is used to treat severe to moderate Alzheimer’s disease. Memantine is an NMDA (N-methyl-D-aspartate) receptor antagonist, which means it works by regulating the activity of glutamate, a neurotransmitter in the brain involved in learning and memory.

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Mechanism of Action 

Memantine acts by blocking NMDA receptors. These receptors, if activated by glutamate cause brain damage as well as cognitive impairment. In blocking these receptors Memantine assists in normalizing glutamate activity, and could slow the progression of Alzheimer’s-related symptoms.

Indications: 

Admenta 5 mg is prescribed for:

• Treatment of severe to moderate Alzheimer’s disease.

Admenta 5 mg Dosage and Administration:

• The most common dosage for a starting dosage is 5 mg a day.
• The dosage may be gradually increased, generally by 5 mg every week, until you reach the recommended dosage of 20 mg daily (usually taken in 10 mg twice a day).
• It is crucial to follow the instructions for dosing that are provided by a medical professional.

What is a Admenta 5 mg Side Effects?

The most common side effects could include:

• Dizziness
• Headache
• Confusion
• Constipation
• Hypertension

Less frequent, however more severe side effects could include:

• Hallucinations
• Allergic reactions (rash itching and swelling)
• Seizures

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Contraindications:

• Hypersensitivity to Memantine or other ingredient included in the formulation.
• Renal impairment severe (without dose adjustment).

Precautions:

• Take care when using this medication in patients who have an epilepsy history or seizures.
• Patients with severe liver impairment must be closely monitored.
• Some medications can interact with others It is therefore important to inform your medical professional of any medicines you are taking.

Drug Interactions:

• Amantadine and ketamine as well as dextromethorphan can enhance the likelihood of adverse consequences due to similar mechanisms of operation.
• The use of medications that alter the pH of urine (like sodium bicarbonate) can alter the levels of Memantine in blood.
• Be cautious with other NMDA antagonists.

Pregnancy and Lactation:

• There are no data available regarding the effects of memantine in pregnancy. It should only be used in cases where the potential benefit is greater than the risk to the foetus.
• It isn’t known whether Memantine is excreted in human milk. Therefore caution must be taken when administering Memantine to nursing mothers.

Storage:

• Keep Admenta 5 mg at room temperature (25degC).
• Keep away from the reach of children.
• Be sure to shield yourself from light and moisture.

Patient Information:

• Patients should be aware of the possible side effects.
• They should be instructed to use the medication according to instructions and not stop taking it without consulting with their healthcare provider.
• A regular follow-up visit is vital to track the progression of the disease and adjust the dosage when necessary.