Axentri 150 mg (Maraviroc)

Description

Axentri 150 mg is a supplement to the active ingredient Maraviroc. Maraviroc is an antiretroviral medicine that is used to treat HIV (human immune deficiency virus) infection. It is a member of the class of drugs called CCR5 antagonists.

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Mechanism of Action

Maraviroc is a drug that blocks the CCR5 receptor located on the surface of some immune cells which HIV utilizes to attack these cells. By blocking HIV from entering cells, Axentri 150 mg (Maraviroc) helps to reduce the amount of virus present in the body, and increases the amount of CD4+ cells (a kind of white blood cells that plays a vital role in maintaining the health of your immune system).

Indications

Axentri 150 mg (Maraviroc) is indicated in conjunction with other antiretroviral drugs to treat CCR5-tropic HIV-1 infections in pediatric and adult patients who are 2 years old or over weighing at least 10 kilograms. It is indicated for patients who have signs of replication as well as HIV forms that are intolerant to multiple antiretroviral medications.

Axentri 150 mg Dosage and Administration

• Children and adults (>=40 kg): The typical dosage is 300 mg twice a day when combined with other antiretroviral medications. However, if the medication is combined alongside other drugs (such as protease inhibitors without the use of ritonavir) the dosage may be adjusted up to either 150 mg or 600 mg a day.
• Children (2 years old or older and weighing more than 10 kg): Dosage is dependent on body weight and whether there are any other medications that are in conjunction with it.

Related Pills:  Atavir 300 mg (Atazanavir) | Aromasin 25mg (Exemestane) | Armotraz 1mg (Anastrozole)

What is a Axentri 150 mg Side Effects?

Common side effects are:

• Infections of the upper respiratory tract
• Cough
• Fever
• Rash
• Musculoskeletal symptoms
• Abdominal pain
• Dizziness

Some serious side effects can include:

• Hepatotoxicity (liver damage)
• Skin rashes and allergic reactions
• Heart attack or stroke

Precautions

• Liver function Check liver enzymes both before and during treatment. Do not stop treatment if symptoms of liver problems begin to show.
• Health and cardiovascular: Take care for patients with a history of heart disease.
• Allergies Check for hypersensitive reactions.

Drug Interactions

Maraviroc is metabolized through the CYP3A4 enzyme, and can interact with drugs that stimulate or inhibit this enzyme for example, certain antifungals, antibiotics such as anticonvulsants, anthelmintics, and other HIV drugs. It is possible to make dosage adjustments.

Contraindications

Axentri 150 mg (Maraviroc) is not recommended in patients suffering from extreme renal impairment or end-stage renal diseases taking powerful CYP3A inhibitors or inducers.

Monitoring

• Regular monitoring of the liver’s function as well as cardiovascular health is advised.
• Regular evaluation of renal function could be required.

Patient Advice

• You should take Axentri 150 mg (Maraviroc) exactly as directed by your doctor.
• Do not alter the dosage or cease using Maraviroc without consulting with your healthcare provider.
• Inform your healthcare provider of any other medications you’re taking, including prescription drugs as well as herbal supplements.

Storage

• Keep at room temperature far from heat and moisture.