Celkeran 2 mg (Chlorambucil)

Description

General Information

• Generic Name: Chlorambucil
• Brand Name: Celkeran
• Dosage Form Oral tablets
• Strength: 2 mg
• Drug Classification: Alkylating agent
• ATC Code: L01AA02

Indications

Celkeran 2 mg (chlorambucil) is used to treat:

• Chronic lymphocytic Leukemia (CLL)
• Malignant lymphoma that includes Hodgkin’s disease as well as non-Hodgkin’s lympho
• Waldenstrom’s macroglobulinemia

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Mechanism of Action

Chlorambucil is an alkylating nitrogen mustard agent. It functions by binding to DNA and disrupting the reproduction of cancerous cells, thereby reducing their growth and causing the death of cells.

Celkeran 2 mg Dosage and Administration

• The dose of chlorambucil can be highly individualized dependent on the kind of cancer being treated the patient’s weight and general health.
• The standard dosage for CLL is 0.1 to 0.2 mg/kg body weight per day during 3 to 6 weeks.
• For lymphomas that are malignant, the dosage can vary, and is usually administered in cycles.
• Celkeran tablets should be taken orally along with the aid of a glass of water. They can be consumed without or with food.
• A regular blood test is necessary to check the amount of blood cells in the blood and organ performance.

What is a Celkeran 2 mg Side Effects?

Common side effects of chlorambucil include:

• Bone Marrow suppression (leading to low blood cell counts)
• Gastrointestinal symptoms (nausea, vomiting, diarrhea)
• Mouth sores
• Hair loss (alopecia)
• Fatigue
• Allergic reactions or rashes

The most serious side effects could include:

• Bone marrow suppression severe
• Risk of infection is increased because of low white blood cells count
• Liver toxicity
• Malignancies that are secondary (development of cancerous new cells)

Related Pills:  Cassotide 50 mg (Bicalutamide) | Capegard 500 mg (Capecitabine) | Calutide 50 mg (Bicalutamide)

Precautions and Warnings

• Chlorambucil may cause significant bone marrow loss; regular surveillance of blood cell count is essential.
• It can harm an unborn baby Pregnant women should not take the medication, and a reliable contraception is recommended.
• It is not recommended to breastfeed during treatment.
• Patients suffering from kidney or liver dysfunction may require dosage adjustments as well as closely monitored.
• Be aware of older patients who are more prone to adverse side effects.

Drug Interactions

• Chlorambucil is a drug that can interact with other medicines that cause bone marrow loss and increase the chance of serious adverse reactions.
• It could be a potential interaction with vaccines, reducing their effectiveness or increasing the possibility of developing reactions that are adverse.
• Inform your doctor of any medications or supplements you are taking to prevent possible interactions.

Storage

• Keep Celkeran tablets at room temperature away from heat and moisture.
• Keep away from the children’s reach.

Emergency/Overdose

• In the event of an overdose, get medical assistance.
• Overdose symptoms can include vomiting, nausea diarrhea, extreme fatigue due to bone marrow deficiency.

Patient Information

• Inform your healthcare provider of any symptoms of bleeding, swelling, bleeding, or any other serious adverse reactions to your doctor immediately.
• Regular check-ups and blood tests are required to evaluate the effectiveness and security of treatment.